A team of filmmakers take a tour of South America with mural artist and animator Blu, looking to see how his art and mind will be influenced through total immersion in foreign cultures. The team traveled through Mexico, Guatemala, Nicaragua Costa Rica and Argentina, and named the film after those countries. In the director's words, "What came out was an unscripted film about improvisation, inspiration (and perspiration), innovation, self-exploration and all the other good things in life that end with -ion."